abstract：:The purpose was to compare the short-term cost-effectiveness of intensive vs conventional education and supervision for the self-management of mild asthmatic patients. Consecutive newly diagnosed asthmatic patients (n = 162) were randomized into an intervention group (IG) and a control group (CG) with 1 yr of treatmen...

journal_title：Respiratory medicine

authors： Kauppinen R,Sintonen H,Tukiainen H

更新日期：1998-02-01 00:00:00

abstract：:Obstructive sleep apnoea syndrome (OSAS) has acute and chronic effects on the cardiovascular system. Both right and left sides of the heart are affected. Electrocardiographic pattern was studied in 190 OSAS patients. One or more of the following were found: persistent deep S in lateral chest leads V5, V6 (79%), left a...

journal_title：Respiratory medicine

authors： Khalil MM,Rifaie OA

更新日期：1998-01-01 00:00:00

abstract：:Long-term oxygen therapy (LTOT) in patients with chronic hypoxaemia is an expanding field. Traditional stationary oxygen, with and without portable compressed gas cylinders, and portable liquid oxygen equipment is available today. No official guidelines exist for the prescription of liquid oxygen vs traditional oxygen...

journal_title：Respiratory medicine

authors： Schaanning J,Strøm K,Boe J

更新日期：1998-01-01 00:00:00

abstract：:Assessment of asthma severity is important for disease management. Analysis of symptoms past and present, and previous and actual lung function measurements (including variability) is the usual method of evaluation and classification of asthma disease severity and activity. However, symptoms and lung function alterati...

journal_title：Respiratory medicine

authors： Dahl R,Martinati LC,Boner AL

更新日期：1997-11-01 00:00:00

abstract：:It has been hypothesized that hepatocyte growth factor (HGF) may play an important role in regulating the growth of lung epithelium and in the regeneration of the lung as a paracrine or endocrine factor in idiopathic pulmonary fibrosis (IPF). Based on this background, serum HGF was measured in 31 IPF patients (21 male...

journal_title：Respiratory medicine

authors： Hojo S,Fujita J,Yoshinouchi T,Yamanouchi H,Kamei T,Yamadori I,Otsuki Y,Ueda N,Takahara J

更新日期：1997-10-01 00:00:00

abstract：:Synovial sarcoma most commonly occurs in the peri-articular regions of the extremities. The present report describes a rare case of primary biphasic synovial sarcoma of the pleura in an 18-year-old female. The diagnosis was made on the basis of light microscopy, immunohistochemistry, electron microscopy and the charac...

journal_title：Respiratory medicine

authors： Jawahar DA,Vuletin JC,Gorecki P,Persechino F,Macera M,Magazeh P

更新日期：1997-10-01 00:00:00

abstract：:The diagnostic value of isocapnic hyperventilation of cold air (IHCA) is not fully established. All 342 adult patients in whom IHCA had been performed because of a clinical suspicion of asthma between 1992 and 1994 were analysed retrospectively in the authors' hospital. In addition, 26 healthy subjects were recruited....

journal_title：Respiratory medicine

authors： Koskela HO,Räsänen SH,Tukiainen HO

更新日期：1997-09-01 00:00:00

abstract：:In 16 patients with pulmonary fibrosis, an artificial pneumothorax was introduced using the Veress cannula and the Saugman water manometer. Atmospheric air was introduced by fractionated insufflation to a total volume of 800 ml (median). The interpleural space was found on the first attempt, and in all cases, fraction...

journal_title：Respiratory medicine

authors： Faurschou P,Viskum K

更新日期：1997-08-01 00:00:00

abstract：:The results of pulmonary function testing with a turbine spirometer (TS) and a bell spirometer (BS) of a randomized group of 275 patients aged 4-18 years were compared. In the TS, an inexpensive device without graphical display was used. The difference BS minus TS (d) for forced expiratory volume in 1 s (FEV1) was cal...

journal_title：Respiratory medicine

authors： Paul KP,Schultz T

更新日期：1997-07-01 00:00:00

abstract：:The Spacehaler is a new, compact, pressurized aerosol device that uses the same canister as a conventional metered-dose inhaler (MDI). Its design, however, reduces the velocity of the aerosol cloud that emerges from the inhaler, thereby reducing the amount of the non-respirable fraction of the drug delivered to the pa...

journal_title：Respiratory medicine

authors： Gunawardena KA,Sohal T,Jones JI,Upchurch FC,Crompton GK

更新日期：1997-05-01 00:00:00

abstract：:A case of endobronchial metastasis 2 yr following treatment of rectal carcinoma is presented. Endobronchial metastases from extrathoracic primary malignancies are uncommon, the estimated frequency and possible mechanisms underlying this complication are discussed. The importance of recognizing possible endobronchial m...

journal_title：Respiratory medicine

authors： Lee YC,Wong CS,Jeffery GM

更新日期：1997-04-01 00:00:00

abstract：:Epithelioid haemangioendothelioma of the pulmonary vessels is a rare neoplasm which usually has a minimal clinical expression. The present case report describes an exceptional case with severe inaugural alveolar haemorrhage which led to death by acute respiratory failure within a few weeks. ...

journal_title：Respiratory medicine

authors： Briens E,Caulet-Maugendre S,Desrues B,Quinquenel ML,Lena H,Turlin B,Delaval P

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:The prevalence of asthma appears to be on the increase, and risk factors are not well established. To investigate risk factors for the development of asthma, a population sample of children and adolescents, aged 7-17 years at enrolment, were studied in 1986. Initial examinations were repeated at follow-up in...

journal_title：Respiratory medicine

authors： Ulrik CS,Backer V,Hesse B,Dirksen A

更新日期：1996-11-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is now the most common indication for single lung transplantation. In long-term follow-up, obliterative bronchiolitis is a major problem. The aim of the present study was to perform a long-term follow-up of the pulmonary function and to examine the effect of development of ...

journal_title：Respiratory medicine

authors： Bjørtuft O,Geiran OR,Fjeld J,Skovlund E,Johansen B,Boe J

更新日期：1996-10-01 00:00:00

abstract：:The efficacy of a non-steroidal anti-inflammatory agent (nedocromil sodium, NS) has been assessed in young children born prematurely who had recurrent respiratory symptoms at follow-up. In a randomized, double-blind cross-over trial, either two puffs of NS (2 mg puff-1) or placebo were administered three times a day v...

journal_title：Respiratory medicine

authors： Yüksel B,Greenough A

更新日期：1996-09-01 00:00:00

abstract：:Patients using domiciliary nasal ventilation, or long-term oxygen, require regular assessment which could be carried out in the home. Blood gas analysis may be regarded as an essential part of the assessment. The present study investigated the effect of a 1-h time delay on the measurement of capillary blood gases. Fou...

journal_title：Respiratory medicine

authors： Bird CM,Revill SM,Vara DD,Morgan MD

更新日期：1996-02-01 00:00:00

abstract：:The aims of this study were to describe asthma management and morbidity in patients attending general practitioners in Australia, and to assess the relationship between patient reports and those of their general practitioner (GP). The sample comprised consecutive patients attending 46 general practitioners chosen at r...

journal_title：Respiratory medicine

authors： Bauman A,Cooper C,Bridges-Webb C,Tse M,Miles D,Bhasale A,Pollock M

更新日期：1995-11-01 00:00:00

abstract：:Ulcerative colitis is one of the few diseases in which smoking appears to confer some benefit (1). We report a patient whose ulcerative colitis deteriorated on several occasions on stopping cigarettes, and improved on restarting smoking. As a result, she continued smoking despite developing airflow limitation and seve...

journal_title：Respiratory medicine

authors： Watson JP,Lewis RA

更新日期：1995-10-01 00:00:00

abstract：:Recombinant human DNase I (rhDNase) has been shown to improve pulmonary function in patients treated for up to 6 months. A cohort of 52 cystic fibrosis patients with a FVC > 40% predicted were enrolled into an open label study in order to evaluate longer-term effects of rhDNase. They received 2.5 mg rhDNase twice dail...

journal_title：Respiratory medicine

authors： Shah PL,Scott SF,Geddes DM,Hodson ME

更新日期：1995-08-01 00:00:00

abstract：:The objective of this study was to compare bronchial challenge tests with two substances [histamine (H) and methacholine (M)] and two methods of measuring the effect parameter FEV1 and pulmonary impedance [with the forced oscillation technique (FOT)] in order to determine which test is the shortest, and gives the leas...

journal_title：Respiratory medicine

authors： Weersink EJ,vd Elshout FJ,van Herwaarden CV,Folgering H

更新日期：1995-05-01 00:00:00

abstract：:The objective of this study was to evaluate the effect of lateral body position on gas exchange in patients with unilateral pleural effusion, with special reference to the influence of effusion volume. Thirty consecutive patients with unilateral pleural effusion, without evidence of parenchymal pulmonary involvement, ...

journal_title：Respiratory medicine

authors： Romero S,Martín C,Hernández L,Arriero JM,Benito N,Gil J

更新日期：1995-04-01 00:00:00

abstract：:During an epidemiological investigation of asthma in an occupational setting, 1126 subjects completed a modified Medical Research Council respiratory questionnaire, then underwent airway responsiveness measurements as PD20FEV1 to methacholine. Previous experience of bronchoconstriction was assessed in the 481 subjects...

journal_title：Respiratory medicine

authors： Stenton SC,Beach JR,Avery AJ,Hendrick DJ

更新日期：1995-03-01 00:00:00

abstract：:Invasive pulmonary aspergillosis is a frequent complication in immunocompromised patients. The role of the prolonged use of steroids in predisposing to invasive aspergillosis has been recognized, but exceptionally described in asthmatic patients. We report the case of a 59-year-old woman with bronchial asthma treated ...

journal_title：Respiratory medicine

authors： Ganassini A,Cazzadori A

更新日期：1995-02-01 00:00:00

abstract：:A survey was undertaken to determine the current practice in the Yorkshire Health Region for the assessment and provision of home nebulizers for adults with chronic obstructive pulmonary disease (COPD). A detailed postal questionnaire on assessment methods was sent to each of the 22 consultant physicians in respirator...

journal_title：Respiratory medicine

authors： Hosker HS,Teale C,Greenstone MA,Muers MF

更新日期：1995-01-01 00:00:00

abstract：:Oxygen therapy for use in the home can be prescribed in two forms: oxygen concentrators are used to provide long term domiciliary oxygen therapy (LTOT), and oxygen cylinders are used to provide oxygen intermittently for relief of symptoms. In this study prescription and usage of oxygen cylinders in the home were asses...

journal_title：Respiratory medicine

authors： Okubadejo AA,Paul EA,Wedzicha JA

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:We have observed that Doctors often perceive that cystic fibrosis (CF) is exceptionally rare in non-whites, and that this bias has repeatedly resulted in diagnostic delay. We therefore compared the age at diagnosis, genetic features and relative prevalence of CF in non-whites and white patients in the West M...

journal_title：Respiratory medicine

authors： Spencer DA,Venkataraman M,Higgins S,Stevenson K,Weller PH

更新日期：1994-10-01 00:00:00

abstract：:Preterm infants who are symptomatic at follow-up frequently have a high airways resistance (RAW) and a low functional residual capacity to thoracic gas volume ratio (FRC:TGV). The aim of this study was to assess the effect of bronchodilator therapy on these lung function abnormalities. Thirty-four infants who had recu...

journal_title：Respiratory medicine

authors： Yuksel B,Greenough A

更新日期：1994-04-01 00:00:00

abstract：:The records of a total of 497 patients notified to have active tuberculosis (TB) in Western Australia from 1986 to 1990 inclusive have been reviewed in relation to case-finding. Of these, 276 (55.5%) were Asian migrants, 92 (18.5%) Europeans and 110 (22.1%) Australians. The disease was confirmed bacteriologically in 2...

journal_title：Respiratory medicine

authors： Pang SC,Harrison RH,Clayton AS,Mercer J,Brearley J

更新日期：1994-03-01 00:00:00

abstract：:We have analysed the clinical manifestations of nine patients with brief upper airway dysfunction (BUAD) who attended the thoracic department of a major teaching hospital between 1987 and 1991. Episodes of BUAD developed within 1-4 months of presentation in three patients but were undiagnosed for 2.5-12.5 years in six...

journal_title：Respiratory medicine

authors： Campbell AH,Pierce R

更新日期：1994-02-01 00:00:00

abstract：:The measurement of CA50 in serum and pleural fluid by immunoradiometric assay was presented in 45 (27 malignancy and 18 tuberculosis) patients with pleural effusion. The mean CA50 level in malignant effusion (89.26 +/- 122.32 U ml-1) was significantly higher than that in tuberculous effusion (5.18 +/- 8.65 U ml-1) (P ...

journal_title：Respiratory medicine

authors： Yang SZ,Ji SQ

更新日期：1994-01-01 00:00:00

abstract：:Pneumocystis carinii colonization was studied in 90 men using the polymerase chain reaction. These comprised ten heterosexual controls; ten HIV-seronegative homosexual controls; 20 HIV-seropositive homosexuals with blood CD4 count > 400 x 10(6) l-1; 20 HIV-seropositive homosexuals with CD4 < 400 x 10(6) l-1; ten HIV-s...

journal_title：Respiratory medicine

authors： Leigh TR,Kangro HO,Gazzard BG,Jeffries DJ,Collins JV

更新日期：1993-10-01 00:00:00

abstract：:In patients with asthma, exercise-induced symptoms are well recognized and frequently limiting. Currently available beta 2-receptor agonists have a short duration of action and breakthrough symptoms may occur. We studied the efficacy of the recently developed long acting inhaled beta 2-agonist salmeterol with respect ...

journal_title：Respiratory medicine

authors： Newnham DM,Ingram CG,Earnshaw J,Palmer JB,Dhillon DP

更新日期：1993-08-01 00:00:00

abstract：:Malnutrition may be an extremely important complicating factor in patients with a variety of chronic lung diseases. The impact of malnutrition on lung disease and respiratory muscle function has been extensively studied in patients with chronic lung disease due to cystic fibrosis (CF). In patients with CF it appears t...

journal_title：Respiratory medicine

authors： Heijerman HG

更新日期：1993-08-01 00:00:00

abstract：:Ten patients (two male) suffering from acute exacerbations of long-standing chronic obstructive pulmonary disease and admitted in hypoxic, hypercapnic respiratory failure were treated with Nasal Intermittent Positive Pressure Ventilation (NIPPV) plus supplemental oxygen, on a general medical ward. The median (range) p...

journal_title：Respiratory medicine

authors： Conway JH,Hitchcock RA,Godfrey RC,Carroll MP

更新日期：1993-07-01 00:00:00

abstract：:The prevalence of preferential nasal breathing was studied in an awake adult population. One hundred and ninety-four people consented to gentle manual compression of the nostrils. They were advised to 'breathe in and out', but no further information regarding breathing was given to avoid influencing the patient. One h...

journal_title：Respiratory medicine

authors： Ward KA,Nicholls DP,Stanford CF

更新日期：1993-05-01 00:00:00

abstract：:This retrospective study reviews the patterns of P. cepacia pulmonary infection in 75 of a total of 872 mainly adults with cystic fibrosis, registered here during the 4 years 1987-1990; 35 (47%) were female. During this period, 55 patients acquired P. cepacia and the annual incidence and prevalence rates have remained...

journal_title：Respiratory medicine

authors： Taylor RF,Gaya H,Hodson ME

更新日期：1993-04-01 00:00:00

abstract：:A survey was conducted in a metropolitan suburb to examine family clusters of pulmonary tuberculosis patients and related factors. Firstly, a descriptive study was done based on the review of tuberculosis registration cards over a 11-yr period. Of 1106 cases, 109 (9.9%) were found to occur in households which had alre...

journal_title：Respiratory medicine

authors： Kondo T,Hotta I,Yamanaka K,Sakakibara H,Miyao M,Yamada S

更新日期：1993-04-01 00:00:00

abstract：:Total lung capacity was measured in 16 workers with pulmonary asbestosis using four standard methods: body plethysmography, radiographic lung area, helium dilution by multiple breath and by single breath (alveolar volume). All men had irregular opacities of ILO profusion category 2/1 or greater and four had pleural pl...

journal_title：Respiratory medicine

authors： Kilburn KH,Miller A,Warshaw RH

更新日期：1993-02-01 00:00:00

abstract：:The pathophysiology of corticosteroid-induced osteoporosis is complex, but centres around a primary inhibition of osteoblastic activity compounded by the effects of secondary hyperparathyroidism. The preservation of the microanatomy of bone in the early stages of the disease, coupled with strategies to prevent the eme...

journal_title：Respiratory medicine

authors： Hosking DJ

更新日期：1993-02-01 00:00:00

abstract：:Although in the clinic the presence of mucus in the airways is known to be an important factor influencing the sound of coughing in pathological conditions, this observation has not been established experimentally. We have substituted mucus in the airways of anaesthetized cats with 0.5 ml of natural undiluted egg albu...

journal_title：Respiratory medicine

authors： Korpás J,Widdicombe JG,Vrabec M

更新日期：1993-01-01 00:00:00